Leishmania is the adroit abettor of leishmanioses. The abounding breed of the
brand Leishmania pathogenic to bodies do not appearance morphological
differences. They can be differentiated on the base of biological criteria,
class analyzes the altered analytic pictures and epidemiological facts (see
tab.).
Leishmania are transmitted by changeable mosquitoes of the genera Phlebotomus
and Lutzomyia (?sandflies?), that action in warmer regions of countries in Asia,
Africa, Europe (Mediterranean countries) and Latin America. The amastigote
stages of the bacteria ingested by the insect with a claret meal are adapted in
its civil into slender, bang promastigote forms, which accumulate and drift
aback into the proboscis. When adulterated sandflies yield addition bloodmeal
the promastigote forms are inoculated into a new host (humans or added
vertebrates).
In the host the promastigotes bound (within 12-14 hours) transform into
amastigote stages, which again appear in a action akin exocytosis and can affect
new cells. In cutaneous and mucocutaneous leishmanioses the parasites about
abide belted to the derma or derma and mucosa. Cutaneous leishmanioses lesions
may abide for continued periods, but tend to alleviate spontaneously, admitting
a greater addiction to annihilative changes is apparent in mucocutaneous
leishmanioses infections. By adverse in belly leishmanioses the animal can
access the absolute mononuclear phagocytic arrangement in assorted organs
(spleen, liver, lymph, nodes, cartilage marrow, claret monocytes etc.), causing
infections that are commonly baleful after treatment.
from:
http://pengpengzheng.blog.com/2013/01/14/what-is-leishmania-elisa/
