Ronidazole is a
nitroimidazole antibiotic/antiprotozoal from the aforementioned ancestors as
metronidazole. It is baneful to protozoa by advantage of the disruption of
protozoal DNA. Ronidazole is appreciably added able than metronidazole in
alleviative trichomonal infections. There is aswell some analysis that
indicates that it may be able to amusement Giardia in dogs.
Most of the biologic
interactions listed for ronidazole are extrapolated from acquaintance with
metronidazole.
Ronidazole may access the
levels of the afterward drugs: cyclosporine, systemic tacrolimus, fluorouacil,
lithium.
Cimetidine, and ketoconazole
abatement the metabolism of ronidazole, and could access the accident of
neurotoxicity.
Ronidazole should not be acclimated
with oxytetracyclines, phenobarbital, rifampin, or phenytoin. These drugs
either antagonize, or access the metabolism of ronidazole.
Alcohol should be abhorred
due to the achievability of a disulfiram reaction.
Ronidazole should be abhorred
in animals accepting coumarin anticoagulants due to added array times.
