Macitentan Description

CAS: 441798-33-0

Molecular Formula: C19H20Br2N6O4S

Molecular weight:588.27

Macitentan was accustomed in October 2013. It is adumbrated for patients with pulmonary arterial hypertension, and is marketed beneath the cast name Opsumit. Macitentan is an antagonist/blocker of endothelin receptors on claret argosy and bland muscle, and, thus, blocks the dispatch of vasculature hypertrophy, inflammation, fibrosis, proliferation, and vasoconstriction. Similar to all drugs acting on the renin-angiotensin system, macitentan is associated with antecedent and fetal toxicity, so it should not be used in abundance and has appropriate precautions that have to be followed for all females of changeable age.