CAS
No.: 474657-72-2
Molecular
Formula: C16H21BrN2.HCl
Molecular
Weight: 357.72
Solubility:Soluble
to 100 mM in DMSO and to 10 mM in water with gentle warming
Desformylflustrabromine hydrochloride is a absolute allosteric modulator of α4β2 nicotinic
acetylcholine receptors (nAChRs). It is additionally acclaimed to selectively
access the ionic known through α4β2 in the attendance of ACh (acetylcholine).
Desformylflustrabromine hydrochloride shows a 14-fold selectivity of α4β2
against α7, homomeric receptors is aswell observed. Other studies agenda the
affectation of abstinent cytotoxicity in HCT-116 corpuscle cultures.
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