2015/02/12

Cerebroside Structure



The axiological anatomy of a cerebroside is ceramide. Monoglycosyl and oligoglycosylceramides accepting a address or polysaccharide affirmed glycosidically to the terminal OH accumulation of ceramide are authentic as cerebrosides. Sphingosine is the capital long-chain abject present in ceramide.
Galactosylceramide is the arch glycosphingolipid in academician tissue. Galactosylceramides are present in all afraid tissues, and can compose up to 2% dry weight of blah amount and 12% of white matter. They are above capacity of oligodendrocytes. Glucosylceramide is begin at low levels in beastly beef such as the spleen, erythrocytes, and afraid tissues, abnormally neurons. Glucosylceramide is a above basic of derma lipids, area it is capital for lamellar physique accumulation in the degree corneum and to advance the baptize permeability barrier of the skin. Glucosylceramide is the alone glycosphingolipid accepted to plants, fungi and animals. It is usually advised to be the arch glycosphingolipid in plants. It is a above basic of the alien band of the claret membrane. Galactosylceramides accept not been begin in plants.
Monogalactosylceramide is the better individual basic of the myelin sheath of nerves. Cerebroside amalgam can accordingly accord a altitude of myelin accumulation or remyelination. The amoroso atom is affiliated glycosidically to the C-1 hydroxyl accumulation of ceramide, such as in lactosylceramide. Cerebrosides absolute a sulfuric ester (sulfate) group, accepted as sulfatides, aswell action in the myelin sheath of nerves. These compounds are finer called as sulfates of the ancestor glycosphingolipid.
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