2018/01/30

Aucubin Description


Aucubin is begin in accepted verbena. Aucubin is a monoterpenoid based compound. Aucubin, like all iridoids, has a cyclopentan-[C]-pyran skeleton. Iridoids can abide of ten, nine, or rarely eight carbons in which C11 is added frequently missing than C10. Aucubin has 10 carbons with the C11 carbon missing. The stereochemical configurations at C5 and C9 advance to cis alloyed rings, which are accepted to all iridoids absolute carbocylclic- or seco-skeleton in non-rearranged form. Oxidative break at C7-C8 band affords secoiridoids. The endure accomplish in the biosynthesis of iridoids usually abide of O-glycosylation and O-alkylation. Aucubin, a glycoside iridoid, has an O-linked glucose moiety. Aucubin is an iridoid glycoside. Iridoids are frequently begin in plants and action as arresting compounds. Irioids abatement the advance ante of abounding generalist herbivores. Aucubin is begin in the leaves of Aucuba japonica (Cornaceae), Eucommia ulmoides (Eucommiaceae), and Plantago asiatic (Plantaginaceae), etc, plants used in acceptable Chinese and folk medicine. Aucubin was begin to assure adjoin alarmist accident induced by carbon tetrachloride or alpha-amanitin in mice and rats if 80 mg/kg was dosed intraperitoneally. Geranyl pyrophosphate is the forerunner for iridoids.
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