What is Oltipraz ?

Oltipraz is a synthetic, commissioned 1,2-dithiole-3-thione ahead acclimated in bodies as an antischistosomal agent. Cruciferous vegetables accommodate several agents, including dithiolethiones, which arise to arrest carcinogenesis; however, it is cryptic which comestible compounds aftermath the careful effects. Animal studies accept approved that oltipraz is a almighty inducer of Appearance II detoxification enzymes, a lot of conspicuously glutathione-S-transferase (GST).

Oltipraz is a constructed dithiolethione with abeyant chemopreventive and anti-angiogenic properties. Oltipraz induces appearance II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H:quinone oxidoreductase 1 (NQO1). The consecration of detoxification enzymes enhances the detoxification of assertive cancer-causing agents, thereby acceptable their abolishment and preventing carcinogen-induced DNA damages. Although the exact apparatus through which the anti-angiogenesis aftereffect charcoal to be absolutely elucidated, oltipraz maybe able to attune the announcement of a amount of angiogenic factors, thereby blocking the abiding and focal neovascularization in assorted bump cell types.

Oltipraz has been acclimated in trials belief the analysis and blockage of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.