Miglitol is an articulate anti-diabetic
biologic that acts by inhibiting the adeptness of the accommodating to breach
down circuitous carbohydrates into glucose. It is primarily acclimated in
diabetes mellitus blazon 2 for establishing greater glycemic ascendancy by
preventing the assimilation of carbohydrates (such as disaccharides,
oligosaccharides, and polysaccharides) into monosaccharides which can be
captivated by the body.
Miglitol, and added structurally-related
iminosugars, arrest glycoside hydrolase enzymes alleged alpha-glucosidases.
Since miglitol works by preventing assimilation of carbohydrates, it lowers the
bulk of postprandial hyperglycemia. It accept to be taken at the alpha of
capital commons to accept acute effect. Its aftereffect will depend on the bulk
of non-monosaccharide carbohydrates in a person's diet.
In adverse to acarbose (another
alpha-glucosidase inhibitor), miglitol is systemically absorbed; however, it is
not metabolized and is excreted by the kidneys.
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