CAS no.: 557795-19-4
Molecular Formula: C22H27FN4O2
Molecular Weight: 398.47
Product description:
Sunitinib is a Kinase Inhibitor. The
apparatus of action of sunitinib is as a Protein Kinase Inhibitor.
Sunitinib is an indolinone acquired and
tyrosine kinase inhibitor with abeyant antineoplastic activity. Sunitinib
blocks the tyrosine kinase activities of vascular endothelial advance agency
receptor 2 (VEGFR2), platelet-derived advance agency receptor b (PDGFRb), and
c-kit, thereby inhibiting angiogenesis and corpuscle proliferation. This
abettor aswell inhibits the phosphorylation of Fms-related tyrosine kinase 3
(FLT3), addition receptor tyrosine kinase bidding by some leukemic cells.
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