Glabridin whitening effect and inhibit the formation of melanin

In Yokota et al. Responsible for a comprehensive experiment to test a light licorice and anti-inflammatory effect of melanin, and also studied the structure and effectiveness glabridin relationship. To test the light licorice whitening activity of guinea pig experiments using UV light brown back, and then with 0.5% Glabridin smear test. Found Glabridin can significantly reduce the UV radiation caused by the pigmentation, but also for the applied research area of the skin, this part of the skin coated with 0.1% dopa, calculated by the optical microscope where every square millimeter area of ​​dopa positive response to the number of melanocytes. To estimate the light licorice ability to inhibit the formation of melanin. Can be found through the surface tissue of the treatment group's dopa-positive melanocytes decreased, the use of light licorice can increase the skin's luster. The researchers concluded that licorice root not only in the light licorice can inhibit melanin formation, but also anti-inflammatory. Also observed Glabridin of these effects and its chemical structure.
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Glabridin pharmacological effects